Midazolam

Midazolam is a benzodiazepine drug used for anesthesia, surgical sedation, sleeping disorders, and extreme agitation. It functions by inducing drowsiness, reducing anxiety, and triggering a loss of the ability to construct new memory. The drug may be injected into a muscle or through the mouth, intravenously, or sprayed through the nose and cheeks. If administered intravenously, it typically begins work in five minutes.

Long-term use of epilepsy treatment is not advised as a significant side effect from sedation because of the significant possibility of resistance (which ineffectualizes midazolam and other benzodiazepines). The anticonvulsant effect progresses quickly and the dosage will have to be increased many times in order to maintain the therapeutic effects of anti-epileptic drugs. There are downsides, including a high degree of seizing in over 50% of those diagnosed and medication failures in 14 to 18% of patients with the refractory epileptic disease.